SCHEMBL19441640

SCHEMBL19441640

C[C@@H](O)[C@@H](O)[C@H](CO[C@H]1OC(CF)[C@@H](O)C(O)C1O)NC(=O)CCCCCCCCCCc1ccc(Oc2ccc(F)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SELP P16109 11/20 0.40
▸ SLC5A1 P13866 4/20 0.34
▸ SLC5A2 P31639 4/20 0.34
▸ PPARG P37231 1/20 0.34
▸ PPARD Q03181 1/20 0.34
▸ PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20870247 1.00 SELP (0.40) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL21757439 0.94 PPARG (0.41) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL19441496 0.94 PPARG (0.41) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL20870541 0.94 PPARG (0.41) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL19818859 0.94 PPARG (0.41) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL16559174 0.90 SELP (0.44) SELP
SCHEMBL19441497 0.90 SELP (0.43) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL21167735 0.90 SELP (0.43) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL20870540 0.90 SELP (0.43) SELPSLC5A1SLC5A2PPARGPPARD
SCHEMBL20870546 0.89 SELP (0.39) SELPSLC5A1SLC5A2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10918714-B2 Human iNKT cell activation using glycolipids with altered glycosyl groups ACADEMIA SINICA (TW) 2021-02-16 — — US disclosed
US-9879042-B2 Human iNKT cell activation using glycolipids ACADEMIA SINICA (TW) 2018-01-30 — — US disclosed
US-9782476-B2 Human iNKT cell activation using glycolipids with altered glycosyl groups ACADEMIA SINICA (TW) 2017-10-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10918714-B2 Human iNKT cell activation using glycolipids with altered glycosyl groups UGCG, GALK1, B3GAT3 SELP 722/4885SLC5A1 341/4885SLC5A2 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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