SCHEMBL19442893

SCHEMBL19442893

CNC(=O)[C@H](CC(=O)O)NC(=O)Cc1ccc(CNC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17900826 0.91 FOLH1 (0.58) FOLH1
SCHEMBL22300022 0.90 FOLH1 (0.63) FOLH1
SCHEMBL20346890 0.90 FOLH1 (0.60) FOLH1
SCHEMBL15739424 0.89 FOLH1 (0.58) FOLH1
SCHEMBL17191797 0.89 FOLH1 (0.58) FOLH1
SCHEMBL15739387 0.89 FOLH1 (0.58) FOLH1
SCHEMBL18311344 0.89 FOLH1 (0.58) FOLH1
SCHEMBL24491184 0.89 FOLH1 (0.55) FOLH1
SCHEMBL18800243 0.89 FOLH1 (0.55) FOLH1
SCHEMBL18800212 0.88 FOLH1 (0.57) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9782493-B2 Conjugates for treating diseases caused by PSMA expressing cells ENDOCYTE, INC. (US) 2017-10-10 — — US disclosed
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