Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.38 |
| ▸ | NPY4R | P50391 | 6/20 | 0.38 |
| ▸ | NPY1R | P25929 | 5/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263117 | 0.94 | HDAC1 (0.42) | NPC1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL10260131 | 0.93 | NPY4R (0.43) | NPY5RNPY4RNPY1RNPY2RHDAC1 | |
| SCHEMBL19445627 | 0.92 | NPC1 (0.39) | NPC1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL19445529 | 0.92 | NPY4R (0.42) | NPY5RNPY4RNPY1RNPY2RHDAC1 | |
| SCHEMBL19445747 | 0.92 | NPY4R (0.37) | NPC1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL10262456 | 0.91 | NPY4R (0.45) | NPY5RNPY4RNPY1RNPY2RHDAC1 | |
| SCHEMBL19485986 | 0.90 | NPC1 (0.45) | NPC1HDAC1HDAC3EGFRHDAC4 | |
| SCHEMBL12515239 | 0.90 | NPY4R (0.37) | NPC1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL19445632 | 0.89 | NPY4R (0.40) | NPC1NPY5RNPY4RNPY1RNPY2R | |
| SCHEMBL10262202 | 0.89 | NPY4R (0.43) | NPY5RNPY4RNPY1RNPY2RHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |