Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 11/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 10/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515364 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL12515355 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL10260969 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL19445724 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL21371991 | 0.99 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL21371923 | 0.99 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL21371992 | 0.99 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL19945119 | 0.99 | ERAP2 (0.47) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL19445847 | 0.95 | ERAP2 (0.45) | ERAP2LNPEPERAP1HDAC3HDAC4 | |
| SCHEMBL12517112 | 0.95 | ERAP2 (0.45) | ERAP2LNPEPERAP1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |