Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.54 |
| ▸ | CCR6 | P51684 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423478 | 0.83 | CXCR2 (0.74) | CXCR2CCR6 | |
| SCHEMBL2293989 | 0.83 | CXCR2 (0.74) | CXCR2CCR6 | |
| SCHEMBL15936064 | 0.81 | CXCR2 (0.57) | CXCR2CCR6 | |
| SCHEMBL2300075 | 0.79 | CXCR2 (0.70) | CXCR2CCR6 | |
| SCHEMBL2300081 | 0.79 | CXCR2 (0.70) | CXCR2CCR6 | |
| SCHEMBL2298386 | 0.78 | CXCR2 (0.69) | CXCR2CCR6 | |
| SCHEMBL2299001 | 0.77 | CXCR2 (0.67) | CXCR2CCR6 | |
| SCHEMBL2293247 | 0.77 | CXCR2 (0.67) | CXCR2CCR6 | |
| SCHEMBL20761610 | 0.77 | CCR6 (0.70) | CCR6 | |
| SCHEMBL2293856 | 0.77 | CXCR2 (0.67) | CXCR2CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760821-B1 | CHOLINE SALT OF AN ANTI-INFLAMMATORY SUBSTITUTED CYCLOBUTENEDIONE COMPOUND | NOVARTIS AG (CH) | 2017-10-11 | — | — | EP | disclosed |