Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.57 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | BRAF | P15056 | 4/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.42 |
| ▸ | CDK9 | P50750 | 9/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065013 | 0.89 | CSF1R (0.62) | CSF1RFYNBRAF | |
| SCHEMBL12064807 | 0.89 | CCNT1 (0.54) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL12698727 | 0.88 | CCNC (0.60) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL5203867 | 0.88 | CCNC (0.60) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL12064718 | 0.88 | CCNT1 (0.54) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL12065366 | 0.88 | CSF1R (0.51) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL19447150 | 0.88 | CSF1R (0.71) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL19447242 | 0.86 | BRAF (0.48) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL12064822 | 0.86 | FYN (0.52) | CSF1RCCNCCDK8FYNBRAF | |
| SCHEMBL12065015 | 0.86 | CSF1R (0.58) | CSF1RCCNCCDK8FYNBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848610-B1 | Inhibitors of kinase activity | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2017-10-11 | — | — | EP | disclosed |