Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 15/20 | 0.63 |
| ▸ | RET | P07949 | 1/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.63 |
| ▸ | KIT | P10721 | 1/20 | 0.63 |
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.63 |
| ▸ | FLT1 | P17948 | 1/20 | 0.63 |
| ▸ | FLT4 | P35916 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.63 |
| ▸ | FRK | P42685 | 1/20 | 0.63 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | LDHB | P07195 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13340215 | 1.00 | CSF1R (0.63) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL19447205 | 0.92 | CSF1R (0.63) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340090 | 0.92 | CSF1R (0.63) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340085 | 0.91 | CSF1R (0.61) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL19447128 | 0.91 | CSF1R (0.61) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340272 | 0.89 | CSF1R (0.65) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL19447192 | 0.86 | CSF1R (0.61) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340266 | 0.86 | CSF1R (0.61) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340035 | 0.86 | CSF1R (0.63) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL19447236 | 0.86 | CSF1R (0.63) | CSF1RRETPDGFRBKITSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848610-B1 | Inhibitors of kinase activity | YM BIOSCIENCES AUSTRALIA PTY (AU) | 2017-10-11 | — | — | EP | disclosed |