Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15072873 | 1.00 | KMT2A (0.37) | KMT2AGRM5HCRTR1HCRTR2PDE2A | |
| SCHEMBL15072883 | 0.94 | GRM5 (0.39) | KMT2AGRM5PDE2A | |
| SCHEMBL15072930 | 0.94 | KMT2A (0.36) | KMT2AGRM5HCRTR1HCRTR2 | |
| SCHEMBL2738251 | 0.93 | HCRTR1 (0.38) | KMT2AGRM5HCRTR1HCRTR2PDE2A | |
| SCHEMBL19447243 | 0.93 | GRM5 (0.44) | KMT2AGRM5HCRTR1HCRTR2 | |
| SCHEMBL15072882 | 0.93 | GRM5 (0.44) | KMT2AGRM5HCRTR1HCRTR2 | |
| SCHEMBL2737738 | 0.92 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL15072971 | 0.92 | HCRTR1 (0.39) | KMT2AGRM5HCRTR1HCRTR2 | |
| SCHEMBL17445223 | 0.92 | HCRTR1 (0.37) | KMT2AGRM5HCRTR1HCRTR2 | |
| SCHEMBL15077264 | 0.91 | GRM5 (0.37) | GRM5HCRTR1HCRTR2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |