Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15073051 | 1.00 | HCRTR1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL18023427 | 0.94 | HCRTR1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL19447543 | 0.94 | HCRTR1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL15072876 | 0.94 | HCRTR1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL19447291 | 0.94 | HCRTR1 (0.40) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL2737696 | 0.93 | HSP90AA1 (0.38) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL2737739 | 0.93 | MAPT (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL2738268 | 0.93 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL2738236 | 0.92 | HCRTR1 (0.39) | HCRTR1HCRTR2HSP90AA1HSP90AB1 | |
| SCHEMBL15073090 | 0.92 | HCRTR1 (0.38) | HCRTR1HCRTR2HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |