Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16945095 | 0.78 | CNR2 (0.53) | CNR2OPRK1NOS3NOS1NOS2 | |
| SCHEMBL12991619 | 0.75 | CNR2 (0.50) | CNR2OPRK1NOS3NOS1NOS2 | |
| SCHEMBL20468863 | 0.73 | OGA (0.45) | OGAHSD17B10ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL20134764 | 0.71 | ACVR1 (0.41) | OGA | |
| SCHEMBL19151000 | 0.70 | OGA (0.34) | OGAOPRK1 | |
| SCHEMBL23228690 | 0.69 | HSD17B10 (0.40) | HSD17B10ALDH1A1CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL2366129 | 0.69 | TAAR1 (0.47) | CYP2D6CYP1A2CYP3A4TSHR | |
| SCHEMBL19446958 | 0.69 | HRH4 (0.48) | ALDH1A1CYP2D6CYP1A2CYP3A4TSHR | |
| SCHEMBL20468950 | 0.69 | ACACB (0.52) | OGAHSD17B10ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL20618427 | 0.68 | CYP3A4 (0.35) | OGAOPRK1CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175000-A1 | COMPOUNDS | PULMOCIDE LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |