Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 13/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 13/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 13/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1944281 | 0.99 | CHRM4 (0.71) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL13908459 | 0.88 | CHRM4 (0.60) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL1943328 | 0.86 | CHRM4 (0.58) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL3008239 | 0.84 | CHRM4 (1.00) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL3008242 | 0.84 | CHRM4 (1.00) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL3022257 | 0.83 | CHRM4 (0.98) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL3022258 | 0.83 | CHRM4 (0.98) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL3017139 | 0.82 | CHRM4 (0.82) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL3017134 | 0.82 | CHRM4 (0.82) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL3010335 | 0.81 | CHRM4 (0.80) | CHRM4CHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344000-B2 | Compounds which have activity at M1 receptor and their uses in medicine | GLAXO GROUP LIMITED (GB) | 2013-01-01 | — | — | US | claimed |
| US-20110130423-A1 | Compounds Which Have Activity At M1 Receptor And Their Uses In Medicine | GLAXO GROUP LIMITED, | 2011-06-02 | — | — | US | claimed |
| EP-2197441-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | Glaxo Group Limited (GB) | 2010-06-23 | — | — | EP | claimed |
| WO-2009037293-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-03-26 | — | — | WO | claimed |
| US-8344000-B2 | Compounds which have activity at M1 receptor and their uses in medicine | GLAXO GROUP LIMITED (GB) | 2013-01-01 | — | — | US | disclosed |
| US-8344000-B2 | Compounds which have activity at M1 receptor and their uses in medicine | GLAXO GROUP LIMITED (GB) | 2013-01-01 | — | — | US | disclosed |
| US-8344000-B2 | Compounds which have activity at M1 receptor and their uses in medicine | GLAXO GROUP LIMITED (GB) | 2013-01-01 | — | — | US | disclosed |
| US-20110130423-A1 | Compounds Which Have Activity At M1 Receptor And Their Uses In Medicine | GLAXO GROUP LIMITED, | 2011-06-02 | — | — | US | disclosed |
| US-20110130423-A1 | Compounds Which Have Activity At M1 Receptor And Their Uses In Medicine | GLAXO GROUP LIMITED, | 2011-06-02 | — | — | US | disclosed |
| US-20110130423-A1 | Compounds Which Have Activity At M1 Receptor And Their Uses In Medicine | GLAXO GROUP LIMITED, | 2011-06-02 | — | — | US | disclosed |
| WO-2009037293-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130423-A1 | Compounds Which Have Activity At M1 Receptor And Their Uses In Medicine | CHRM1, CHRM2, CHRM5 | CHRM4 4/4885CHRM5 3/4885CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.