Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 14/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456704 | 0.87 | MALT1 (0.35) | SLC22A12MALT1 | |
| SCHEMBL19456736 | 0.77 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL19456883 | 0.73 | SLC22A12 (0.44) | SLC22A12 | |
| SCHEMBL19456711 | 0.72 | SLC22A12 (0.49) | SLC22A12 | |
| SCHEMBL19456726 | 0.70 | SLC22A12 (0.41) | SLC22A12 | |
| SCHEMBL19456708 | 0.69 | GRIN2D (0.34) | MALT1 | |
| SCHEMBL19456819 | 0.68 | SLC22A12 (0.56) | SLC22A12 | |
| SCHEMBL19456742 | 0.66 | SLC22A12 (0.50) | SLC22A12 | |
| SCHEMBL19456738 | 0.65 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL19456733 | 0.65 | SLC22A12 (0.50) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |