Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 19/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456744 | 0.86 | SLC22A12 (0.62) | SLC22A12 | |
| SCHEMBL19456722 | 0.74 | SLC22A12 (0.60) | SLC22A12 | |
| SCHEMBL19456726 | 0.72 | SLC22A12 (0.41) | SLC22A12 | |
| SCHEMBL12070783 | 0.71 | SLC22A12 (1.00) | SLC22A12 | |
| SCHEMBL19456742 | 0.68 | SLC22A12 (0.50) | SLC22A12 | |
| SCHEMBL18970753 | 0.68 | SLC22A12 (0.57) | SLC22A12 | |
| SCHEMBL18703717 | 0.67 | CYP17A1 (0.45) | TGFBR1 | |
| SCHEMBL19456883 | 0.66 | SLC22A12 (0.44) | SLC22A12 | |
| SCHEMBL19456738 | 0.66 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL17899926 | 0.65 | SLC22A12 (0.47) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173965-A1 | NOVEL URAT1 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2017-10-12 | — | — | WO | disclosed |