Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19457708 | 0.91 | USP30 (0.45) | L3MBTL1MEN1KMT2AUSP30ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL19639843 | 0.89 | SCN9A (0.40) | KCNJ1 | |
| Trifluoroacetic Acid SCHEMBL19639842 | 0.89 | MEN1 (0.42) | L3MBTL1MAPTNPSR1MAPK1MEN1 | |
| SCHEMBL19473772 | 0.84 | KCNJ1 (0.41) | KCNJ1 | |
| SCHEMBL19457848 | 0.82 | KCNJ1 (0.53) | L3MBTL1MAPTNPSR1USP30NSD2 | |
| Trifluoroacetic Acid SCHEMBL19457877 | 0.81 | KCNJ1 (0.48) | KCNJ1 | |
| SCHEMBL19639844 | 0.81 | KCNJ1 (0.45) | USP30KCNJ1 | |
| SCHEMBL19473769 | 0.80 | NSD2 (0.52) | L3MBTL1MEN1KMT2APOLBUSP30 | |
| SCHEMBL19473757 | 0.79 | USP30 (0.46) | L3MBTL1MEN1KMT2APOLBUSP30 | |
| Trifluoroacetic Acid SCHEMBL19457704 | 0.76 | CDK4 (0.39) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231802-B1 | PYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2021-05-05 | — | — | EP | disclosed |
| EP-3231802-A1 | PYRIDINECARBOXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2017-10-18 | — | — | EP | disclosed |