SCHEMBL19459042

SCHEMBL19459042

Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)O[C@@H]4[C@@H](O)[C@H](n5cnc6c(=O)[nH]c(N)nc65)O[C@@H]4COP(=O)(O)O[C@H]3[C@H]2N)c(=O)[nH]1

nearest known ligand 0.91

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 18/20 0.91
▸ PDE3B Q13370 1/20 0.91
▸ PDE3A Q14432 1/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19491654 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL18963754 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL18963689 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL19502704 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL19503140 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL23350871 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL18963752 1.00 STING1 (0.91) STING1PDE3BPDE3A
SCHEMBL12671632 0.96 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL17974376 0.96 STING1 (1.00) STING1PDE3BPDE3A
SCHEMBL21498373 0.96 STING1 (1.00) STING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210139604-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF OPI VI - IP HOLDCO LLC 2021-05-13 — — US disclosed
US-20170298139-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF OPI VI - IP HOLDCO LLC 2017-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170298139-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF STING1, CGAS, TLR7 STING1 1/4885PDE3B 488/4885PDE3A 581/4885
US-20210139604-A1 COMPOSITIONS OF ANTIBODY CONSTRUCT-AGONIST CONJUGATES AND METHODS OF USE THEREOF STING1, CGAS, TLR7 STING1 1/4885PDE3B 488/4885PDE3A 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback