SCHEMBL19459581

SCHEMBL19459581

C[C@H](CC(=O)O)OC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 9/20 0.38
NPY1R P25929 6/20 0.38
NPY2R P49146 4/20 0.35
NPY5R Q15761 4/20 0.35
ITGB3 P05106 5/20 0.35
ITGA2B P08514 5/20 0.35
DPP7 Q9UHL4 1/20 0.34
OTC P00480 1/20 0.34
DDAH1 O94760 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28276618 1.00 NPY4R (0.38) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL28275413 0.99 NPY4R (0.37) NPY4RNPY1RNPY2RNPY5RITGB3
SCHEMBL28038714 0.89 DPP7 (0.36) ITGB3ITGA2BDPP7OTCDDAH1
SCHEMBL23408857 0.86 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL15459530 0.86 NPY4R (0.39) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL5635045 0.84 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL7782784 0.84 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL7782787 0.84 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL12921582 0.84 DPP7 (0.47) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL577171 0.84 OTC (0.37) NPY4RNPY1RNPY2RNPY5RITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226043-A1 ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC 2024-07-11 US disclosed
US-11969411-B2 Administration of berberine metabolites AXCESS GLOBAL SCIENCES, LLC (US) 2024-04-30 US disclosed
EP-3445355-B1 BETA-HYDROXYBUTYRATE FOR USE IN NON-THERAPEUTIC METHODS OF CONTROLLING WEIGHT LOSS AND KETOTIS AXCESS GLOBAL SCIENCES LLC (US) 2023-11-29 EP disclosed
US-20230346723-A1 ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC 2023-11-02 US disclosed
WO-2023212319-A1 ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE SALT BLEND AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC (US) 2023-11-02 WO disclosed
WO-2023081409-A1 ADMINISTRATION OF BERBERINE METABOLITES Keto Patent Group, Inc. (US) 2023-05-11 WO disclosed
US-20220202789-A1 ADMINISTRATION OF BERBERINE METABOLITES AXCESS GLOBAL SCIENCES, LLC 2022-06-30 US disclosed
US-20220047578-A1 ADMINISTRATION OF BERBERINE METABOLITES AXCESS GLOBAL SCIENCES, LLC 2022-02-17 US disclosed
US-20210393560-A1 ADMINISTRATION OF R-BETA-HYDROXYBUTYRATE AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC 2021-12-23 US disclosed
US-11173138-B2 Administration of butyrate, beta-hydroxybutyrate, and related compounds in humans Keto Patent Group, Inc. (US) 2021-11-16 US disclosed
EP-3873442-A1 ADMINISTRATION OF BUTYRATE, BETE-HYDROXYBUTYRATE, CANNABIDIOL, AND RELATED COMPOUNDS IN HUMANS Keto Patent Group, Inc. (US) 2021-09-08 EP disclosed
US-20200129463-A1 ADMINISTRATION OF BUTYRATE, BETA-HYDROXYBUTYRATE, CANNABIDIOL, AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC 2020-04-30 US disclosed
WO-2017184788-A1 ADMINISTRATION OF BUTYRATE, BETA-HYDROXYBUTYRATE, AND RELATED COMPOUNDS IN HUMANS Keto Patent Group, Inc. (US) 2017-10-26 WO disclosed
US-20170296501-A1 ADMINISTRATION OF BUTYRATE, BETA-HYDROXYBUTYRATE, AND RELATED COMPOUNDS IN HUMANS AXCESS GLOBAL SCIENCES, LLC 2017-10-19 US disclosed