Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 16/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946202 | 0.88 | PNP (0.44) | PNP | |
| SCHEMBL1947653 | 0.80 | PNP (0.56) | PNP | |
| SCHEMBL14495696 | 0.80 | PNP (0.56) | PNP | |
| SCHEMBL1946850 | 0.75 | PNP (0.56) | PNP | |
| SCHEMBL1946189 | 0.74 | PNP (0.64) | PNP | |
| SCHEMBL1945322 | 0.74 | PNP (0.64) | PNP | |
| SCHEMBL1946798 | 0.74 | PNP (0.64) | PNP | |
| SCHEMBL20579151 | 0.74 | PNP (0.66) | PNP | |
| SCHEMBL1415816 | 0.74 | PNP (0.66) | PNP | |
| SCHEMBL1415658 | 0.74 | PNP (0.66) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | claimed |
| EP-2395005-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | Industrial Research Limited (NZ) | 2011-12-14 | — | — | EP | claimed |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | BIOCRYST PHARMACEUTICALS, INC. | 2011-06-02 | — | — | US | claimed |
| WO-2008030119-A9 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-09-24 | — | — | WO | claimed |
| WO-2009082247-A1 | PROCESS FOR PREPARING IMMUCILLINS HAVING A METHYLENE LINK | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-07-02 | — | — | WO | claimed |
| EP-2057165-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-05-13 | — | — | EP | claimed |
| WO-2008030119-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | claimed |
| US-10918641-B2 | Use of MTAP inhibitors for the treatment of lung disease | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2021-02-16 | — | — | US | disclosed |
| US-20180353511-A1 | Use of MTAP Inhibitors for the Treatment of Lung Disease | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. | 2018-12-13 | — | — | US | disclosed |
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| EP-2395005-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | Industrial Research Limited (NZ) | 2011-12-14 | — | — | EP | disclosed |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | BIOCRYST PHARMACEUTICALS, INC. | 2011-06-02 | — | — | US | disclosed |
| WO-2009082247-A1 | PROCESS FOR PREPARING IMMUCILLINS HAVING A METHYLENE LINK | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180353511-A1 | Use of MTAP Inhibitors for the Treatment of Lung Disease | MTAP, TYMP, TPMT | PNP 5/4885 |
| US-20110130412-A1 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | PNP, TYMP, NTPCR | PNP 1/4885 |
| US-10918641-B2 | Use of MTAP inhibitors for the treatment of lung disease | MTAP, TYMP, TPMT | PNP 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.