Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28765244 | 1.00 | DEPTOR (0.47) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29597278 | 1.00 | DEPTOR (0.47) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL22968457 | 0.81 | DEPTOR (0.46) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29596251 | 0.81 | DEPTOR (0.46) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL32681965 | 0.78 | GAA (0.47) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28765243 | 0.78 | GAA (0.47) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL680401 | 0.77 | GAA (0.45) | KMT2AMEN1RAB9ANPC1CA9 | |
| SCHEMBL680400 | 0.77 | GAA (0.45) | KMT2AMEN1RAB9ANPC1CA9 | |
| SCHEMBL22968440 | 0.77 | DEPTOR (0.43) | DEPTORKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29711854 | 0.77 | DEPTOR (0.43) | DEPTORKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555603-B | Improved synthetic methods for preparing (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-114555603-A | Improved synthesis for the preparation of (2H-1,2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114555603-B | Improved synthetic methods for preparing (2H-1, 2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2025-03-14 | — | — | CN | disclosed |
| EP-4010325-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1,2,3-TRIAZOL-2-YL)PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-06-15 | — | — | EP | disclosed |
| CN-114555603-A | Improved synthesis for the preparation of (2H-1,2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021023843-A1 | IMPROVED SYNTHETIC METHODS OF MAKING (2H-1,2,3-TRIAZOL-2-YL)PHENYL COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-02-11 | — | — | WO | disclosed |
| US-20110130406-A1 | PYRAZOLO-PYRIDINES AS TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130406-A1 | PYRAZOLO-PYRIDINES AS TYROSINE KINASE INHIBITORS | TYRO3, LCK, LTK | DEPTOR 3086/4885KMT2A 3787/4885MEN1 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.