Trifloxysulfuron

Trifloxysulfuron

SCHEMBL19463553

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2OCC(F)(F)F)n1.c1cc[n+]2c(c1)-c1cccc[n+]1CC2

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
MAPT P10636 2/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
CDK1 P06493 1/20 0.35
KDM4E B2RXH2 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 1/20 0.33
S1PR1 P21453 1/20 0.33
KMT2A Q03164 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
XBP1 P17861 1/20 0.32
STAT3 P40763 1/20 0.32
MDM2 Q00987 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifloxysulfuron SCHEMBL15449154 0.89 GAA (0.55) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL64184 0.89 GAA (0.55) GAAMAPTTP53GLACDK1
Flazasulfuron SCHEMBL19463988 0.89 GAA (0.46) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL301007 0.88 GAA (0.54) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL14768215 0.88 GAA (0.53) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL19464006 0.84 GAA (0.43) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL2439050 0.83 GAA (0.47) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL14300670 0.79 GAA (0.44) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL15881938 0.79 GAA (0.44) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL17274486 0.78 GAA (0.43) GAAMAPTTP53GLACDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed