Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Foramsulfuron SCHEMBL7059948 | 0.87 | CDK1 (0.63) | CDK1ALDH1A1GAAMEN1KMT2A | |
| Nicosulfuron SCHEMBL18115226 | 0.84 | TP53 (0.49) | CDK1TP53TDP1ALDH1A1CYP3A4 | |
| Foramsulfuron SCHEMBL116874 | 0.81 | CDK1 (1.00) | CDK1TP53GAAMEN1KMT2A | |
| Foramsulfuron SCHEMBL29419146 | 0.81 | CDK1 (1.00) | CDK1TP53GAAMEN1KMT2A | |
| Foramsulfuron SCHEMBL7060560 | 0.81 | CDK1 (0.55) | CDK1ALDH1A1MEN1KMT2A | |
| Foramsulfuron SCHEMBL2973354 | 0.80 | CDK1 (0.98) | CDK1TP53ALDH1A1GAAMEN1 | |
| Foramsulfuron SCHEMBL2320828 | 0.80 | CDK1 (0.98) | CDK1TP53GAAMEN1KMT2A | |
| Foramsulfuron SCHEMBL15936497 | 0.79 | CDK1 (0.94) | CDK1TP53GAAMEN1KMT2A | |
| Foramsulfuron SCHEMBL7053909 | 0.78 | CDK1 (0.52) | CDK1ALDH1A1MEN1KMT2A | |
| Rimsulfuron SCHEMBL19463429 | 0.78 | TP53 (0.50) | CDK1TP53TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442962-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | Syngenta Participations AG (CH) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178582-A1 | HERBICIDAL PYRIDAZINONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-19 | — | — | WO | disclosed |