⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677484 | 0.74 | — | — | |
| SCHEMBL5208831 | 0.74 | — | — | |
| SCHEMBL895450 | 0.74 | — | — | |
| SCHEMBL5800970 | 0.74 | — | — | |
| SCHEMBL5798424 | 0.74 | — | — | |
| SCHEMBL1679806 | 0.70 | — | — | |
| SCHEMBL1672168 | 0.70 | — | — | |
| SCHEMBL10675525 | 0.69 | — | — | |
| SCHEMBL4755835 | 0.66 | NPC1 (0.48) | — | |
| SCHEMBL6438179 | 0.65 | MAPK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980888-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | claimed |
| US-20140378447-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | claimed |
| EP-0343894-B1 | BENZAMIDE PROTEASE INHIBITORS | PFIZER INC. (US) | 1992-06-10 | — | — | EP | claimed |
| US-4948891-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | claimed |
| EP-0343894-A1 | Benzamide protease inhibitors | PFIZER INC. (US) | 1989-11-29 | — | — | EP | claimed |
| US-4323569-A | β-Lactam anti-bacterial, compositions containing them and a process for their preparation | BEECHAM GROUP LIMITED (GB) | 1982-04-06 | — | — | US | claimed |
| JP-2017177-A | — | — | None | — | — | JP | disclosed |
| CN-106957317-B | Novel pyrazole derivatives | 持田制药株式会社 | 2019-12-31 | — | — | CN | disclosed |
| US-20190071441-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-03-07 | — | — | US | disclosed |
| US-10174025-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20180099964-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-12 | — | — | US | disclosed |
| US-9920030-B2 | Fungicidal azocyclic amides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9902723-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-02-27 | — | — | US | disclosed |
| US-4948901-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| US-4948891-A | ANTI-PLASMIN AND ANTI-THROMBIN AGENTS | PFIZER INC. (US) | 1990-08-14 | — | — | US | disclosed |
| JP-H0217177-A | BENZAMIDE TYPE PROTEASE INHIBITOR | PFIZER INC | 1990-01-22 | — | — | JP | disclosed |
| EP-0343894-A1 | Benzamide protease inhibitors | PFIZER INC. (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4874864-A | ANTIPLASMIN, ANTITHROMBIN AGENTS | PFIZER INC. (US) | 1989-10-17 | — | — | US | disclosed |
| US-4323569-A | β-Lactam anti-bacterial, compositions containing them and a process for their preparation | BEECHAM GROUP LIMITED (GB) | 1982-04-06 | — | — | US | disclosed |
| EP-0008514-B1 | BETA-LACTAM ANTI-BACTERIALS, COMPOSITIONS CONTAINING THEM AND A PROCESS FOR THEIR PREPARATION | BEECHAM GROUP PLC (GB) | 1982-01-20 | — | — | EP | disclosed |