Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486368 | 0.89 | FFAR1 (0.65) | FFAR1 | |
| SCHEMBL19734275 | 0.85 | FFAR1 (0.71) | FFAR1 | |
| SCHEMBL17669380 | 0.84 | FFAR1 (1.00) | FFAR1 | |
| SCHEMBL19451048 | 0.84 | FFAR1 (0.77) | FFAR1 | |
| SCHEMBL19464344 | 0.84 | FFAR1 (0.77) | FFAR1 | |
| SCHEMBL17669265 | 0.84 | FFAR1 (1.00) | FFAR1 | |
| SCHEMBL22014084 | 0.83 | FFAR1 (0.63) | FFAR1 | |
| SCHEMBL19734295 | 0.82 | FFAR1 (0.68) | FFAR1 | |
| SCHEMBL19486339 | 0.80 | FFAR1 (0.80) | FFAR1 | |
| SCHEMBL17669473 | 0.80 | FFAR1 (0.60) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790198-B2 | Substituted benzothiophenyl derivatives as GPR40 agonists for the treatment of type II diabetes | JANSSEN PHARMACEUTICA NV (BE) | 2017-10-17 | — | — | US | disclosed |