Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19059881 | 0.76 | CRBN (0.31) | CRBN | |
| SCHEMBL10072428 | 0.71 | — | — | |
| SCHEMBL20124947 | 0.71 | — | — | |
| SCHEMBL23131142 | 0.65 | — | — | |
| SCHEMBL8257990 | 0.65 | — | — | |
| SCHEMBL14041185 | 0.64 | CRBN (0.32) | CRBNTAS2R38 | |
| SCHEMBL14048896 | 0.64 | — | — | |
| SCHEMBL20849730 | 0.64 | — | — | |
| SCHEMBL28127781 | 0.64 | CRBN (0.41) | CRBNNFKB1TAS2R38 | |
| SCHEMBL22623768 | 0.63 | CRBN (0.36) | CRBNTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |