Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 14/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.67 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464929 | 0.99 | P2RY1 (0.68) | P2RY1P2RY2P2RY11HTR2BADORA3 | |
| SCHEMBL19464927 | 0.94 | P2RY1 (0.66) | P2RY1P2RY2HTR2BADORA3HTR2C | |
| SCHEMBL19807534 | 0.92 | P2RY1 (0.79) | P2RY1P2RY2P2RY11HTR2BADORA3 | |
| SCHEMBL19807424 | 0.89 | P2RY1 (0.85) | P2RY1P2RY2P2RY11ENPP1P2RY12 | |
| SCHEMBL19807425 | 0.89 | P2RY1 (0.84) | P2RY1P2RY2P2RY11HTR2BADORA3 | |
| SCHEMBL21710875 | 0.88 | P2RY1 (0.85) | P2RY1P2RY2P2RY11ADORA3ENPP1 | |
| SCHEMBL19464972 | 0.88 | P2RY1 (0.85) | P2RY1P2RY2P2RY11HTR2BADORA3 | |
| SCHEMBL19464971 | 0.86 | P2RY1 (0.83) | P2RY1P2RY2P2RY11ADORA3 | |
| SCHEMBL19807529 | 0.85 | P2RY1 (0.84) | P2RY1P2RY2P2RY11ADORA3P2RX3 | |
| SCHEMBL19807532 | 0.85 | P2RY1 (0.78) | P2RY1P2RY2HTR2BADORA3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789131-B1 | Compounds and methods for treating neurological and cardiovascular conditions | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-17 | — | — | US | disclosed |