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Sugi Predict / Compounds / SCHEMBL19473973

SCHEMBL19473973

SCHEMBL19473973

CC(=O)NCC(=O)NC1CC(=O)NCCCCC(C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(Cc2ccccc2)NC(=O)CNC1=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 18/20 0.58
▸ MC1R Q01726 8/20 0.58
▸ MC3R P41968 4/20 0.55
▸ TSLP Q969D9 2/20 0.54
▸ MC5R P33032 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19473982 0.98 MC4R (0.57) MC4RMC1RMC3RTSLPMC5R
SCHEMBL19473917 0.96 MC4R (0.60) MC4RMC1RMC3RMC5R
SCHEMBL19473948 0.94 MC4R (0.58) MC4RMC1RMC3RMC5R
SCHEMBL19473842 0.94 MC4R (0.58) MC4RMC1RMC3RMC5R
SCHEMBL19473972 0.94 MC4R (0.58) MC4RMC1RMC3RMC5R
SCHEMBL19473861 0.93 MC4R (0.58) MC4RMC1RMC3R
SCHEMBL19473810 0.93 MC4R (0.58) MC4RMC1RMC3R
SCHEMBL19473830 0.92 MC4R (0.57) MC4RMC1RMC3R
SCHEMBL19473976 0.92 MC4R (0.56) MC4RMC1RMC3RMC5R
SCHEMBL19473894 0.91 MC4R (0.57) MC4RMC1RMC3RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440227-B1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2017-10-18 — — EP disclosed
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