Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766021 | 0.88 | TSHR (0.51) | TSHRMAPK1RECQLKDM4EHPGD | |
| SCHEMBL19478141 | 0.81 | MAPK1 (0.42) | TSHRMAPK1RECQLHPGDALDH1A1 | |
| SCHEMBL9785419 | 0.81 | TSHR (0.42) | TSHRMAPK1RECQLKDM4EHPGD | |
| SCHEMBL9766191 | 0.80 | TSHR (0.41) | TSHRMAPK1RECQLKDM4EKMT2A | |
| SCHEMBL9785413 | 0.78 | TSHR (0.40) | TSHRMAPK1RECQLHPGDMAPT | |
| SCHEMBL9766216 | 0.76 | MAPK1 (0.39) | TSHRMAPK1RECQLKDM4EKMT2A | |
| SCHEMBL19478152 | 0.75 | TSHR (0.42) | TSHRMAPK1KDM4EKMT2AHPGD | |
| SCHEMBL9766130 | 0.74 | RECQL (0.38) | TSHRMAPK1RECQLKMT2AMEN1 | |
| SCHEMBL505374 | 0.74 | TSHR (0.52) | TSHRMAPK1RECQLKDM4EKMT2A | |
| SCHEMBL31361047 | 0.74 | TSHR (0.41) | TSHRMAPK1RECQLKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017179568-A1 | ESTER COMPOUND AND USE THEREOF | 大日本除蟲菊株式会社 | 2017-10-19 | — | — | WO | disclosed |