Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 13/20 | 0.59 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15696157 | 0.88 | DRD1 (0.60) | DRD1USP7USP8GRM2CHRNA7 | |
| SCHEMBL19479326 | 0.87 | DRD1 (0.57) | DRD1USP8 | |
| SCHEMBL19479311 | 0.86 | DRD1 (0.52) | DRD1CHRNA7 | |
| SCHEMBL15705493 | 0.85 | DRD1 (0.57) | DRD1USP7USP8EGLN2 | |
| SCHEMBL17200343 | 0.83 | DRD1 (0.55) | DRD1USP7USP8ALDH1A1 | |
| SCHEMBL15666826 | 0.80 | DRD1 (0.51) | DRD1USP7 | |
| SCHEMBL19479327 | 0.77 | DRD1 (0.55) | DRD1 | |
| SCHEMBL19371612 | 0.76 | DRD1 (0.69) | DRD1 | |
| SCHEMBL17291596 | 0.75 | DRD1 (1.00) | DRD1 | |
| SCHEMBL17224039 | 0.75 | DRD1 (0.61) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917216-B1 | HETEROAROMATIC COMPOUNDS AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2017-10-18 | — | — | EP | disclosed |