Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15191996 | 1.00 | UBA1 (0.73) | UBA1UBE2E1 | |
| SCHEMBL18896474 | 1.00 | UBA1 (0.73) | UBA1UBE2E1 | |
| SCHEMBL15191671 | 0.95 | UBA1 (0.77) | UBA1UBE2E1 | |
| SCHEMBL15201941 | 0.95 | UBA1 (0.77) | UBA1UBE2E1 | |
| SCHEMBL15192059 | 0.91 | UBA1 (0.80) | UBA1UBE2E1 | |
| SCHEMBL15198229 | 0.88 | UBA1 (0.74) | UBA1UBE2E1 | |
| SCHEMBL18896475 | 0.87 | UBA1 (0.76) | UBA1UBE2E1 | |
| SCHEMBL15191623 | 0.87 | UBA1 (0.82) | UBA1UBE2E1 | |
| SCHEMBL15191782 | 0.87 | UBA1 (0.76) | UBA1UBE2E1 | |
| SCHEMBL15192453 | 0.87 | UBA1 (0.76) | UBA1UBE2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796725-B2 | Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-9796725-B2 | Pyrazolopyrimidinyl inhibitors of ubiquitin-activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-10-24 | — | — | US | disclosed |