Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 9/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 8/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138633 | 0.91 | LCAT (0.59) | LCAT | |
| SCHEMBL18138632 | 0.91 | LCAT (0.59) | LCAT | |
| SCHEMBL18138634 | 0.91 | LCAT (0.59) | LCAT | |
| SCHEMBL19485560 | 0.89 | LCAT (0.48) | LCAT | |
| SCHEMBL19485357 | 0.89 | LCAT (0.48) | LCAT | |
| SCHEMBL19485562 | 0.88 | LCAT (0.47) | LCAT | |
| SCHEMBL19485356 | 0.85 | LCAT (0.49) | LCATHRH3 | |
| SCHEMBL19485566 | 0.85 | LCAT (0.49) | LCATHRH3 | |
| SCHEMBL19485388 | 0.84 | LCAT (0.49) | LCATHRH3FFAR1ACACB | |
| SCHEMBL19485089 | 0.81 | LCAT (0.50) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796709-B2 | 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |