Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 11/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138520 | 0.88 | LCAT (0.56) | LCAT | |
| SCHEMBL16814305 | 0.88 | LCAT (0.56) | LCAT | |
| SCHEMBL18138521 | 0.88 | LCAT (0.56) | LCAT | |
| SCHEMBL16814293 | 0.88 | LCAT (0.56) | LCAT | |
| SCHEMBL19485356 | 0.81 | LCAT (0.49) | LCAT | |
| SCHEMBL19485562 | 0.81 | LCAT (0.47) | LCAT | |
| SCHEMBL19485389 | 0.81 | LCAT (0.51) | LCAT | |
| SCHEMBL19485355 | 0.81 | LCAT (0.51) | LCAT | |
| SCHEMBL19485566 | 0.81 | LCAT (0.49) | LCAT | |
| SCHEMBL19485364 | 0.81 | LCAT (0.51) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796709-B2 | 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |