Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935219 | 0.83 | LPAR1 (0.57) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL4572575 | 0.83 | LPAR1 (0.57) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL304203 | 0.78 | TDP1 (0.54) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL15385433 | 0.77 | P2RY10 (0.46) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL4572553 | 0.77 | P2RY10 (0.43) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL14417988 | 0.77 | SMN1; SMN2 (0.45) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL14823175 | 0.75 | P2RY10 (0.47) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL18294593 | 0.74 | LPAR5 (0.47) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL13854735 | 0.73 | USP2 (0.41) | LPAR1LPAR5LPAR4LPAR2LPAR3 | |
| SCHEMBL20682445 | 0.73 | P2RY10 (0.43) | LPAR1LPAR5LPAR4LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298083-A1 | NEW IMMUNOSTIMULATORY COMPOUNDS | Bernhard-Nocht-Institut für Tropenmedizin (DE) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298083-A1 | NEW IMMUNOSTIMULATORY COMPOUNDS | NFATC1, TLR5, IL5 | LPAR1 466/4885LPAR5 251/4885LPAR4 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.