Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516339 | 0.98 | KDM4E (0.56) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL12177000 | 0.94 | KDM4E (0.58) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL29450654 | 0.94 | KDM4E (0.58) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL28407438 | 0.94 | KDM4E (0.58) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| Tannin Pyrogallol SCHEMBL20679969 | 0.94 | KDM4E (0.58) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL29873418 | 0.93 | KDM4E (0.67) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL257001 | 0.93 | KDM4E (0.67) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL21414726 | 0.92 | KDM4E (0.56) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL18960646 | 0.92 | KDM4E (0.46) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL15906506 | 0.91 | KDM4E (0.55) | KDM4EL3MBTL1ATMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178864-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-10-19 | — | — | WO | disclosed |