Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.45 |
| ▸ | CCKBR | P32239 | 2/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219797 | 1.00 | MC4R (0.45) | MC4RCCKBRPRKACBERAP2ERAP1 | |
| SCHEMBL13973857 | 0.99 | MC4R (0.46) | MC4RERAP2ERAP1LNPEPNPY1R | |
| SCHEMBL13973837 | 0.99 | MC4R (0.46) | MC4RERAP2ERAP1LNPEPNPY1R | |
| SCHEMBL12514972 | 0.99 | MC4R (0.46) | MC4RERAP2ERAP1LNPEPNPY1R | |
| SCHEMBL13973759 | 0.99 | MC4R (0.46) | MC4RERAP2ERAP1LNPEPNPY1R | |
| SCHEMBL19214489 | 0.96 | MC4R (0.46) | MC4RCCKBRPRKACBERAP2ERAP1 | |
| SCHEMBL12514971 | 0.96 | MC4R (0.44) | MC4RERAP2ERAP1LNPEPIL1RN | |
| SCHEMBL19219795 | 0.95 | MC4R (0.44) | MC4RCCKBRPRKACBERAP2ERAP1 | |
| SCHEMBL17949850 | 0.95 | ERAP2 (0.48) | MC4RERAP2ERAP1LNPEPIL1RN | |
| SCHEMBL19445778 | 0.94 | MAPT (0.41) | MC4RCCKBRPRKACBERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795575-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2017-10-24 | — | — | US | disclosed |