Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486248 | 1.00 | PPARG (0.57) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL7115360 | 1.00 | PPARG (0.57) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL19486253 | 0.89 | SMN1; SMN2 (0.58) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL19486247 | 0.89 | SMN1; SMN2 (0.58) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL19489229 | 0.89 | SMN1; SMN2 (0.58) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL7831123 | 0.86 | PPARG (0.45) | PPARGPPARAPRSS1TMPRSS15PRSS2 | |
| SCHEMBL6298677 | 0.85 | PPARG (0.57) | PPARGPPARAPRSS1PRSS2PRSS3 | |
| SCHEMBL6297032 | 0.85 | PPARG (0.57) | PPARGPPARAPRSS1PRSS2PRSS3 | |
| SCHEMBL6297030 | 0.85 | PPARG (0.57) | PPARGPPARAPRSS1PRSS2PRSS3 | |
| SCHEMBL2230124 | 0.84 | PPARG (0.63) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2018-05-31 | — | — | US | disclosed |
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | DDOST, LBR, STS | PPARG 1390/4885PPARA 670/4885PRSS1 295/4885 |
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | DDOST, LBR, STS | PPARG 1390/4885PPARA 670/4885PRSS1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.