SCHEMBL19486303

SCHEMBL19486303

CC#C[C@H](CC=O)c1ccc(OCc2ccc3scc(-c4ccc(OCC5CCS(=O)(=O)CC5)cc4C)c3c2)nc1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22014085 0.91 FFAR1 (0.84) FFAR1
SCHEMBL17669272 0.90 FFAR1 (1.00) FFAR1
SCHEMBL17669353 0.90 FFAR1 (1.00) FFAR1
SCHEMBL17669393 0.90 FFAR1 (1.00) FFAR1
SCHEMBL17669586 0.89 FFAR1 (0.87) FFAR1
SCHEMBL17669274 0.85 FFAR1 (0.90) FFAR1
SCHEMBL17669351 0.85 FFAR1 (0.90) FFAR1
SCHEMBL17669392 0.85 FFAR1 (0.90) FFAR1
SCHEMBL19486363 0.85 FFAR1 (0.81) FFAR1
SCHEMBL17669585 0.84 FFAR1 (0.79) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017180457-A1 GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2017-10-19 WO disclosed