SCHEMBL19486366

SCHEMBL19486366

CC#CC(CC(=O)O)c1ccc(OCc2ccc3scc(-c4cc(OCCOC)ccc4C)c3c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669516 1.00 FFAR1 (1.00) FFAR1
SCHEMBL17669603 0.94 FFAR1 (1.00) FFAR1
SCHEMBL17669333 0.94 FFAR1 (1.00) FFAR1
SCHEMBL19436091 0.94 FFAR1 (0.88) FFAR1
SCHEMBL19436244 0.93 FFAR1 (0.87) FFAR1
SCHEMBL17669505 0.91 FFAR1 (1.00) FFAR1
SCHEMBL17669558 0.91 FFAR1 (1.00) FFAR1
SCHEMBL17669646 0.91 FFAR1 (1.00) FFAR1
SCHEMBL17669610 0.91 FFAR1 (1.00) FFAR1
SCHEMBL19486365 0.91 FFAR1 (1.00) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017180457-A1 GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2017-10-19 WO disclosed