SCHEMBL19486704

SCHEMBL19486704

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cc(-c5ccccc5)cc(-c5cccc6cccnc56)c4)n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.47
MAPT P10636 2/20 0.43
MMP9 P14780 2/20 0.43
MMP2 P08253 2/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GMNN O75496 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX15 P16050 1/20 0.43
NFKB1 P19838 1/20 0.43
MMP8 P22894 1/20 0.43
CCR1 P32246 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
MMP13 P45452 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327526 1.00 BRD4 (0.47) BRD4MAPTMMP9MMP2TSHR
SCHEMBL18327315 0.98 BRD4 (0.48) BRD4MAPTMMP9MMP2TSHR
SCHEMBL19486747 0.95 NPC1 (0.46) BRD4MAPTMMP9MMP2TSHR
SCHEMBL18325348 0.93 BRD4 (0.43) BRD4MAPTMMP9MMP2TSHR
SCHEMBL18325200 0.93 BRD4 (0.43) BRD4MAPTMMP9MMP2TSHR
SCHEMBL17829454 0.93 BRD4 (0.48) BRD4MAPTMMP9MMP2TSHR
SCHEMBL19486593 0.92 KDM4E (0.48) BRD4MAPTTSHRKDM4ETP53
SCHEMBL19486722 0.92 KDM4E (0.48) BRD4MAPTTSHRKDM4ETP53
SCHEMBL23231227 0.92 BRD4 (0.43) BRD4MAPTMMP9MMP2TSHR
SCHEMBL19486580 0.92 BRD4 (0.43) BRD4MAPTMMP9MMP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017179809-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2017-10-19 WO disclosed