Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948263 | 0.90 | KDM4E (0.43) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1946082 | 0.87 | KDM4E (0.41) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1946586 | 0.86 | KDM4E (0.41) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1560063 | 0.86 | NPSR1 (0.48) | KDM4ESMN1; SMN2ALDH1A1L3MBTL1PDE4B | |
| SCHEMBL12545477 | 0.84 | KDM4E (0.39) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1946097 | 0.84 | KDM4E (0.40) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1561219 | 0.83 | PDE4B (0.44) | KDM4ESMN1; SMN2ALDH1A1PDE4BHSD17B10 | |
| SCHEMBL1948279 | 0.81 | MAPT (0.47) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL1946343 | 0.79 | IKBKB (0.43) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 | |
| SCHEMBL2466251 | 0.79 | KDM4E (0.44) | KDM4ESMN1; SMN2PKMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136666-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2009138712-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136666-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CYP2W1 | KDM4E 2495/4885SMN1; SMN2 2548/4885PKM 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.