Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 2/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374150 | 0.89 | HCRTR1 (0.48) | HCRTR1HCRTR2MAPTPOLBLMNA | |
| SCHEMBL12374152 | 0.89 | HCRTR1 (0.48) | HCRTR1HCRTR2MAPTPOLBLMNA | |
| SCHEMBL13258526 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2TBK1MAPTPOLB | |
| SCHEMBL3047072 | 0.84 | HCRTR1 (0.48) | HCRTR1HCRTR2CPT2CPT1A | |
| SCHEMBL3044486 | 0.84 | HCRTR1 (0.48) | HCRTR1HCRTR2CPT2CPT1A | |
| SCHEMBL19488551 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2TBK1CNR1CNR2 | |
| SCHEMBL12374119 | 0.76 | HCRTR1 (0.45) | HCRTR1HCRTR2MAPTPOLBLMNA | |
| SCHEMBL2277410 | 0.75 | HCRTR1 (0.51) | HCRTR1HCRTR2MAPTCPT2CPT1A | |
| SCHEMBL2277418 | 0.75 | HCRTR1 (0.51) | HCRTR1HCRTR2MAPTCPT2CPT1A | |
| SCHEMBL20221586 | 0.75 | HCRTR1 (0.41) | HCRTR1HCRTR2MAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |