Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488883 | 0.93 | DHODH (0.41) | SCN3ADHODHSCN9APSMB8AAK1 | |
| SCHEMBL19488545 | 0.90 | DHODH (0.36) | SCN3ADHODHSCN9APSMB8HDAC3 | |
| SCHEMBL19488875 | 0.89 | DHODH (0.35) | SCN3ADHODHSCN9APSMB8KDR | |
| SCHEMBL19488329 | 0.86 | HDAC3 (0.38) | SCN3ADHODHSCN9AHDAC3HDAC4 | |
| SCHEMBL22352229 | 0.83 | PSMB8 (0.43) | SCN3ADHODHSCN9APSMB8IKBKB | |
| SCHEMBL12403439 | 0.82 | SCN3A (0.47) | SCN3ADHODHSCN9APSMB8IKBKB | |
| SCHEMBL19488871 | 0.78 | DHODH (0.40) | SCN3ADHODHSCN9APSMB8IKBKB | |
| SCHEMBL14828738 | 0.78 | SCN3A (0.59) | SCN3ADHODHSCN9APSMB8IKBKB | |
| SCHEMBL12489110 | 0.78 | SCN3A (0.59) | SCN3ADHODHSCN9APSMB8IKBKB | |
| SCHEMBL19488647 | 0.77 | KDM4E (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |