SCHEMBL19490307

SCHEMBL19490307

CC(C)C(O)Oc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.55
ESR2 Q92731 6/20 0.55
CYP3A4 P08684 2/20 0.55
AR P10275 2/20 0.55
HPGD P15428 1/20 0.55
TSHR P16473 1/20 0.55
SLC6A2 P23975 1/20 0.55
SLC6A4 P31645 1/20 0.55
HTR6 P50406 1/20 0.55
ESRRG P62508 1/20 0.55
SLC6A3 Q01959 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
RORC P51449 1/20 0.37
SHBG P04278 1/20 0.35
MEN1 O00255 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9457222 0.86 ESR1 (0.59) ESR1ESR2CYP3A4ARHPGD
SCHEMBL19954421 0.84 ESR2 (0.57) ESR1ESR2CYP3A4ARHPGD
SCHEMBL8636388 0.84 ESR1 (0.61) ESR1ESR2CYP3A4ARHPGD
SCHEMBL17024119 0.82 HIF1A (0.42) ESR1ESR2CYP3A4ARHPGD
SCHEMBL13717569 0.81 ESR2 (0.57) ESR1ESR2CYP3A4ARHPGD
Bisphenol A SCHEMBL29419665 0.79 ESR1 (0.80) ESR1ESR2CYP3A4ARHPGD
Bisphenol A SCHEMBL28857248 0.79 ESR1 (0.80) ESR1ESR2CYP3A4ARHPGD
SCHEMBL709832 0.78 ESR1 (0.53) ESR1ESR2CYP3A4ARHPGD
SCHEMBL12050062 0.78 ESR1 (0.53) ESR1ESR2CYP3A4ARHPGD
SCHEMBL333514 0.77 HIF1A (0.45) ESR1ESR2CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10907040-B2 Polycarbonate composition and article comprising same LG CHEM LTD. (KR) 2021-02-02 US disclosed
US-20190330466-A1 POLYCARBONATE COMPOSITION AND ARTICLE COMPRISING SAME LG CHEM, LTD. (KR) 2019-10-31 US disclosed
US-10240037-B2 Polycarbonate-based resin composition and molded article thereof LG CHEM, LTD. (KR) 2019-03-26 US disclosed
US-20170298222-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED ARTICLE THEREOF LG CHEM, LTD. (KR) 2017-10-19 US disclosed