Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.38 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613496 | 0.92 | BTK (0.40) | BTK | |
| SCHEMBL15613747 | 0.87 | BTK (0.48) | BTK | |
| SCHEMBL16886132 | 0.84 | BTK (0.49) | BTK | |
| SCHEMBL15613603 | 0.79 | BTK (0.36) | BTK | |
| SCHEMBL15613607 | 0.79 | BTK (0.36) | BTK | |
| SCHEMBL15613768 | 0.78 | BTK (0.37) | BTKCMKLR1 | |
| SCHEMBL15613606 | 0.78 | BTK (0.37) | BTK | |
| SCHEMBL15613617 | 0.78 | CSF1R (0.34) | BTKCMKLR1 | |
| SCHEMBL15613605 | 0.78 | BTK (0.36) | BTK | |
| SCHEMBL19484826 | 0.77 | BTK (0.49) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |