Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.49 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.49 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 6/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 7/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | HCK | P08631 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 3/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.45 |
| ▸ | CSK | P41240 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490432 | 0.91 | BTK (0.47) | BTK | |
| SCHEMBL19490444 | 0.85 | BTK (0.49) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL19490558 | 0.85 | BTK (0.49) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613549 | 0.85 | BTK (0.51) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL16886130 | 0.84 | BTK (0.50) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613514 | 0.84 | BTK (0.50) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613673 | 0.80 | BTK (0.55) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613544 | 0.80 | BTK (0.49) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613652 | 0.80 | BTK (0.54) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL15613753 | 0.79 | BTK (0.48) | BTKNUDT14NUDT5LCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |