Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 20/20 | 0.48 |
| ▸ | ABL1 | P00519 | 14/20 | 0.48 |
| ▸ | HCK | P08631 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.42 |
| ▸ | PRKDC | P78527 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.40 |
| ▸ | CSK | P41240 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613627 | 0.92 | SRC (0.59) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL15613742 | 0.83 | SRC (0.60) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL16886192 | 0.82 | SRC (0.57) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL15613701 | 0.81 | SRC (0.56) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL15613702 | 0.79 | SRC (0.71) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL15613635 | 0.79 | BTK (0.41) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL16886136 | 0.79 | SRC (0.55) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL16892158 | 0.78 | BTK (0.47) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL15613545 | 0.77 | SRC (0.48) | SRCABL1HCKEGFRPIK3CD | |
| SCHEMBL16769950 | 0.77 | KDR (0.63) | SRCABL1EGFRPIK3CDKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |