SCHEMBL19494773

SCHEMBL19494773

C#CCOCCOc1ccc(Cc2cc([C@H]3O[C@H](CO)[C@@H](O)C(O)[C@H]3O)ccc2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 1.00
SLC5A1 P13866 13/20 1.00
ADRA2A P08913 1/20 0.70
SLC5A11 Q8WWX8 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL302062 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL500488 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL14324871 1.00 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL24105577 0.92 SLC5A2 (0.86) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL20124638 0.90 SLC5A2 (0.81) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL499848 0.90 SLC5A2 (0.81) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL499901 0.90 SLC5A2 (0.81) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL27368116 0.88 SLC5A2 (0.90) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL19494518 0.87 SLC5A2 (0.79) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL14324857 0.87 SLC5A2 (0.79) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187742-B1 (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-BENZYLPHENYL)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL DERIVATIVES FOR USE IN THE TREATMENT OF DIABETES THERACOS SUB LLC (US) 2017-10-25 EP disclosed