SCHEMBL19495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15207893	0.91	SYK (0.43)	JAK2JAK3PTK2CD63SYK
	SCHEMBL19998	0.90	MAPT (0.43)	JAK2JAK3PTK2MAPTKDM4E
	SCHEMBL21119	0.88	JAK2 (0.52)	JAK2JAK3PTK2ALDH1A1GAA
	SCHEMBL19931	0.88	JAK2 (0.50)	JAK2JAK3PTK2ALDH1A1GAA
	SCHEMBL20993	0.87	ROCK1 (0.42)	JAK2JAK3PTK2CD63SYK
	SCHEMBL15206594	0.87	SYK (0.59)	JAK2GAAMAPTCD63SYK
	SCHEMBL15207847	0.87	KCNH2 (0.47)	JAK2JAK3PTK2
	SCHEMBL20159	0.86	SCN9A (0.42)	JAK2JAK3PTK2ALDH1A1GAA
	SCHEMBL15206787	0.86	JAK2 (0.48)	JAK2JAK3PTK2ALDH1A1GAA
	SCHEMBL15208007	0.86	JAK2 (0.48)	JAK2JAK3PTK2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.