Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 6/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364529 | 0.83 | AOC3 (0.64) | AOC3 | |
| SCHEMBL12814253 | 0.80 | AOC3 (0.52) | AOC3 | |
| SCHEMBL10318818 | 0.79 | AOC3 (0.51) | AOC3 | |
| SCHEMBL11360324 | 0.76 | AOC3 (0.49) | AOC3 | |
| SCHEMBL11361016 | 0.71 | AOC3 (0.83) | AOC3 | |
| SCHEMBL19496882 | 0.70 | AOC3 (0.56) | AOC3CNR2KDM4EALDH1A1TSHR | |
| SCHEMBL12812640 | 0.69 | CNR2 (0.45) | AOC3CNR2KDM4EALDH1A1TSHR | |
| SCHEMBL11356126 | 0.69 | GRIN2D (0.51) | AOC3CNR2KDM4EALDH1A1TSHR | |
| SCHEMBL31506090 | 0.67 | AOC3 (0.60) | AOC3SRCMAPT | |
| SCHEMBL26993973 | 0.67 | AOC3 (0.60) | AOC3SRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-B1 | GLYCINE COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-10-25 | — | — | EP | disclosed |