Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20365984 | 1.00 | RARG (0.36) | RARGERN1EGFRPOLBAPEX1 | |
| SCHEMBL21558859 | 0.96 | POLB (0.36) | RARGERN1POLBAPEX1HTT | |
| SCHEMBL19882271 | 0.90 | CTSA (0.41) | RARGERN1EGFRPOLBAPEX1 | |
| SCHEMBL20342951 | 0.89 | RARG (0.38) | RARGERN1EGFRPOLBAPEX1 | |
| SCHEMBL18699599 | 0.89 | RARG (0.38) | RARGERN1EGFRPOLBAPEX1 | |
| SCHEMBL19497715 | 0.87 | CTSA (0.43) | ERN1POLBAPEX1HTTTDP1 | |
| SCHEMBL18472729 | 0.87 | POLB (0.38) | ERN1POLBAPEX1HTTTDP1 | |
| SCHEMBL18473143 | 0.87 | ERN1 (0.42) | ERN1POLBAPEX1HTTTDP1 | |
| SCHEMBL22812352 | 0.85 | EGFR (0.38) | ERN1EGFRMEN1KMT2ABTK | |
| SCHEMBL20842581 | 0.85 | EGFR (0.38) | ERN1EGFRMEN1KMT2ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2837671-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2017-10-25 | — | — | EP | disclosed |