Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420141 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL19499046 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL20250952 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL18568417 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL21086224 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL23730428 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL18490702 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL18584219 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL21207336 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A | |
| SCHEMBL20250948 | 1.00 | MAPK1 (0.48) | MAPK1ANPEPESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796756-B2 | Galactose cluster-pharmacokinetic modulator targeting moiety for siRNA | Arrowhead Pharmaceuticals, Inc. (US) | 2017-10-24 | — | — | US | disclosed |