SCHEMBL1950236

SCHEMBL1950236

c1ccc(Nc2cccc(Nc3cccc(Nc4ccccn4)n3)n2)nc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.64
MEN1 O00255 4/20 0.64
MAPK10 P53779 1/20 0.64
GFER P55789 1/20 0.64
RAB9A P51151 6/20 0.61
NPC1 O15118 5/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
KDM4E B2RXH2 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
ALOX15 P16050 2/20 0.61
LMNA P02545 2/20 0.61
TP53 P04637 2/20 0.61
TSHR P16473 1/20 0.61
ALOX12 P18054 1/20 0.61
HTT P42858 1/20 0.61
KLF5 Q13887 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
MAPT P10636 2/20 0.54
ALPG P10696 1/20 0.54
PIM1 P11309 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897079 1.00 KMT2A (0.64) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL29391624 0.90 KMT2A (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL221242 0.90 KMT2A (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL20919346 0.89 KMT2A (0.57) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL11133606 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL6175584 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
Bromide SCHEMBL28368455 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL4243882 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL6574416 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL30947359 0.87 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110137009-A1 POLYAMIC ACID, POLYIMIDE, MANUFACTURING METHOD THEREOF, AND POLYIMIDE FILM SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-06-09 US disclosed